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Name of Funded Study:Aqueous Humor Dynamic Components that Determine Intraocular Pressure
PhenX Protocols: Current Educational Attainment(PX11001)
Annual Family Income(PX11101)
Current Employment Status(PX11301)
Health Insurance Coverage(PX11501)
Height - Standing Height(PX20703)
Neck Circumference(PX21201)
Weight - Measured Weight(PX21501)
Alcohol - 30-Day Quantity and Frequency(PX30301)
Tobacco - Smoking Status - Adult(PX30602)
Tobacco - 30-Day Quantity and Frequency - Adult(PX30802)
Substances - 30-Day Frequency(PX31301)
Blood Pressure (Adult/Primary)(PX40301)
Caffeine Intake(PX50301)
Pre-existing Conditions Associated with Cancer(PX70801)
Menstrual History(PX101101)
Medication Inventory(PX140301)
Personal History of Type 1 and Type 2 Diabetes(PX140501)
Total Physical Activity - Comprehensive - Adult(PX150702)
Total Physical Activity Screener(PX150901)
Study Acronym:
Principal Investigator:Dr. Sayoko Moroi
Primary Contact Name:Diana Burnett
Primary Contact Email:burnettd@med.umich.edu
Number Participants: 100-499
Grant Number:
Study Stage:
Primary Research Focus:Glaucoma is a major cause of blindness. The inability to predict a patient's IOP response to medications is a critical barrier for the clinician to consistently provide highly effective IOP-based treatments. Current trial-and-error approaches to glaucoma management are inefficient and have not addressed this barrier as there are no predictive factors for drug response. Our long-term goal is to improve outcomes by identifying biomarkers and environmental factors that profile a patient at risk for glaucoma by age-of-onset, rate of disease progression, "poor response" to treatment, and large IOP fluctuation. Our purpose of this research project is to address this critical barrier by focusing on physiological factors that predict IOP response to drugs.
Study Design:
Funding Period:
Registration Date:11-SEP-13