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Name of Funded Study:IRIS - Incorporating Research Into Sight (eMERGE II)
PhenX Protocols: Current Age(PX10101)
Birthplace of Grandparents(PX10401)
Current Address(PX10801)
Current Marital Status(PX10901)
Current Educational Attainment(PX11001)
Current Employment Status(PX11301)
Health Insurance Coverage(PX11501)
Hand Dominance - 12 Years and Older(PX20602)
Height - Self-Reported Height(PX20704)
Weight - Self-Reported Weight(PX21502)
Alcohol - Lifetime Use(PX30101)
Alcohol - Age of First Use(PX30201)
Alcohol - 30-Day Quantity and Frequency(PX30301)
Alcohol - Maximum Drinks in 24 Hours(PX30401)
Alcohol - Lifetime Abuse and Dependence(PX30501)
Tobacco - Smoking Status - Adult(PX30602)
Tobacco - Age of Initiation of Use - Adult(PX30702)
Tobacco - 30-Day Quantity and Frequency - Adult(PX30802)
Tobacco - Age of Offset of Cigarette Use - Adult(PX30902)
Cigarette Nicotine Dependence(PX31001)
Family History of Heart Attack(PX40101)
Characteristics of Current Residence(PX60101)
Current Environmental Tobacco Smoke Exposure(PX60701)
Sibship/Birth Order(PX60801)
Ultraviolet Light Exposure(PX61301)
Hypomania/Mania Symptoms - Adult(PX120402)
Depression - Adult(PX120502)
History of Stroke - Ischemic Infarction and Hemorrhage(PX130301)
Total Physical Activity Screener(PX150901)
Study Acronym:IRIS
Principal Investigator:Catherine A. McCarty, PhD
Primary Contact Name:Terrie Kitchner
Primary Contact Email:kitchner.terrie@mcrf.mfldclin.edu
Number Participants: >1000
Grant Number:
Study Stage: Data submitted to dbGaP or other Repository
Primary Research Focus: The PhenX Toolkit was designed to collect data for some of the PhenX measures known to be associated with age-related cataract. This will demonstrate the utility of the PhenX measures in a large-scale biobank and leverage the resources of eMERGE to facilitate additional gene/environment analyses for cataract. These measures were also chosen to allow collaboration among the PhenX RISING sites. Copies of the PhenX measures were mailed to the 3737 living subjects in PMRP that have GWAS data available and have agreed to be re-contacted. The additional PhenX measures were added to enhance the ability to explore gene-environment interactions associated with cataract.
Study Design: Case control
Funding Period:2011-2012
Registration Date:29-AUG-13